CB Insights today named Plume, the first and largest health tech company built for the transgender community, to its third annual Digital Health 150, which showcases the 150 most promising private digital health companies in the world. This year’s Digital Health 150 was unveiled live during CB Insights’ annual Future of Health event.
The 2021 Digital Health 150 cohort has raised roughly $14.9B in aggregate funding across 522 deals since 2016, and includes startups at various investment stages of development, from early-stage to well-funded unicorns. Companies this year include startups working on data integration & analytics, hybrid virtual / in-person care, digital therapeutics, clinical intelligence, and more.
“This year’s Digital Health 150 is one of our most expansive yet, spotlighting 16 categories including virtual care, clinical trials tech, and workflow automation, as well as adding new categories such as home health tech and computer-aided imaging,” said Brian Lee, SVP of CB Insights’ Intelligence Unit. “Last year’s class has seen more than 20 exits, raised an additional $18.6B in aggregate funding, and announced over 250 partnerships since being recognized, and we’re excited to see the future success of this year’s winners.”
“We’re incredibly proud to be recognized in this year’s Digital Health 150 as it’s a true testament to all the hard work our team has accomplished over the past year,” said Matthew Wetschler, co-founder and CEO of Plume. “CB Insight’s annual list recognizes only the premier healthcare startups in the world, so we’re very honored by the award and are excited about continuing to grow, innovate, and provide new offerings to the trans community in the near future.”
Through an evidence-based approach, the CB Insights research team selected the Digital Health 150 from a pool of over 11,000 companies, including applicants and nominees. They were chosen based on several factors, including data submitted by the companies, company business models and momentum in the market, and Mosaic scores, CB Insights’ proprietary algorithm that measures the overall health and growth potential of private companies.
Plume was included for its work in improving access to holistic gender-affirming care (including gender-affirming hormone therapy and emotional support services) for the transgender community. Co-founded by Dr. Matthew Wetschler and Dr. Jerrica Kirkley, Plume Chief Medical Officer, in 2019, Plume offers a $99 a month subscription where members receive 24/7 access to gender-affirming care, personal consultations, lab monitoring, and letters of support, as well as home delivery of their hormone medications for an additional cost. Despite starting at the onset of the pandemic, Plume has seen tremendous growth since launch, expanding its services to 33 states in the US and receiving a $14M Series A funding round in February 2021 led by Craft Ventures.
2021 Digital Health 150 Investment Highlights:
- Unicorns: 17 of the 150 companies (11%) are valued at or above $1B as of their latest funding rounds.
- Funding trends: In 2021 year-to-date (YTD), these 150 private companies have raised $9.2B in equity funding across 153 deals (as of 11/19/21).
- Mega-rounds: Since 2020, there have been 39 mega-round ($100M+) equity investments to this year’s Digital Health 150, with 31 (79%) of them taking place in 2021 YTD.
- Global representation: 23% of the 2021 Digital Health 150 are based outside the US. After the US, the UK is home to the most Digital Health 150 companies (9), followed by India (4). This year’s winners are based in 18 countries, including China, Israel, Nigeria, Germany, Argentina, and New Zealand.
- Top VC investor: General Catalyst is the most active investor in this year’s Digital Health 150 companies, having invested in 39 deals since 2016.
The Digital Health 150 Companies (in alphabetical order):
- 1upHealth
- 54gene
- Ablacon
- Acclinate
- accuRx
- ACTIV Surgical
- Ada Health
- Adyn
- AKASA
- Allara Health
- Alma
- Altoida
- AppliedVR
- Astarte Medical
- b.well
- Better Health
- Binx Health
- BioIntelliSense
- Birdie
- BrightInsight
- Brightline
- c2i Genomics
- Caption Health
- Caresyntax
- Carrum Health
- Castor EDC
- Cedar
- Centaur Labs
- Circulo
- Cityblock Health
- Clarify Health
- Cleerly
- Cleo
- ClosedLoop.ai
- Cohere Health
- Commure
- Congenica
- Curebase
- DeepScribe
- DiA Imaging Analysis
- eko
- Eleanor Health
- Element5
- Elemy
- Elligo Health Research
- Elucid
- Emocha Mobile Health
- Empathy
- Equip
- Exo
- Field Intelligence
- Folx Health
- Genome Medical
- GYANT
- Happify
- Hawthorne Effect
- Headway
- Health Gorilla
- Hello Heart
- Hinge Health
- Honor Technology
- Innovaccer
- Iterative Scopes
- ixLayer
- Jasper Health
- Kaia Health
- Koa Health
- Komodo Health
- League
- LeanTaaS
- LetsGetChecked
- Limbix
- LinkedCare
- Loop Health
- Lumen
- Lunit
- Mahana Therapeutics
- Medable
- Medically Home Group
- Medly Pharmacy
- MedRhythms
- Memora Health
- Meru Health
- Monogram Health
- mPharma
- NeuroFlow
- Nile AI
- NOCD
- Nym
- ObvioHealth
- Olive
- Ophelia
- Osana
- Oshi Health
- Osmind
- Overjet
- Oviva
- Oxehealth
- Paige.AI
- Papa
- PathAI
- Perspectum
- Phable
- Plume
- Pristyn Care
- Proximie
- Quit Genius
- Qure.ai
- RadAI
- Reify Health
- Rendever
- Ribbon Health
- Rightway
- See-Mode Technologies
- Seer Medical
- Sempre Health
- Seqster
- Shukun Technology
- Sidekick Health
- Soda Health
- Somatus
- Sonde Health
- Spring Health
- Stellar Health
- Stork Club
- Strata Oncology
- Sweetch Health
- Sympatient
- Syntegra
- Tendo Systems
- Theator
- Tia
- Tomorrow Health
- Transcarent
- Tripp
- Truepill
- Twin Health
- uLab Systems
- Ultromics
- Unite Us
- Unmind
- Vesta Healthcare
- Vital
- Vocalis Health
- Vori Health
- Wellsheet
- Wheel
- Woebot Health
- Xealth
- Zeen Health
About CB Insights
CB Insights builds software that enables the world’s best companies to discover, understand, and make technology decisions with confidence. By marrying data, expert insights, and work management tools, clients manage their end-to-end technology decision-making process on CB Insights. To learn more, please visit www.cbinsights.com.
About Plume
Plume is the first health technology company built for the transgender community focused on radically increasing access to care, medication and products for the trans community, supporting a bold, authentic and healthy lifestyle. Its vision is to make gender-affirming care available to anyone, anywhere until it transforms healthcare for every trans life. Plume is currently available to over 90% of the trans population across the United States. To learn more, please visit getplume.co.
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