Press release

Synaptive Medical Reveals Automated White Matter Segmentation Feature for Modus™ Plan Surgical Planning Tool Currently under Development

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Synaptive Medical, a global pioneer in automation and robotics, today
revealed an automated white matter segmentation feature to augment its
ModusTM Plan surgical planning software tool that remains
under development. Modus Plan, previously referred to as BrightMatterTM
Plan, is named to align with the next generation of Synaptive products,
including Modus V, and will be available for purchase this year.

During neurosurgical procedures, it is critical for surgeons to minimize
disruption of white matter, which is organized into bundles that may
correspond to different brain functions and whose particular location
differs on a per-patient basis. Access to tractography, an adjunct to a
surgeon’s anatomical knowledge, provides patient-specific and
potentially life-saving information while planning and performing

Synaptive has the only whole brain tractography tool that is fully
automated, which eliminates the time-consuming, subjective process by
which tractography is otherwise generated, and allows surgeons
unprecedented access to tractography for every procedure they perform.
With Modus Plan, surgeons will have the ability to visualize and
highlight patient-specific bundles of interest instantly, which may
allow surgeons to identify safer surgical approaches, optimizing their

“Modus Plan’s automated tractography technology already allows me to
customize pre-operative plans for each of my patients and minimize the
risk of complications,” said Dr. Sebastian Koga MD, medical director,
Neuroscience Institute, and chairman, Neurosurgery Division, Ochsner
North Shore Region. “Tract segmentation takes our approach one step
further, creating an easy process to illuminate or hide bundles of
interest as needed. This ability enhances my ability to plan delicate
surgical approaches for tumors or other pathology.”

“Surgical technology should adapt to the surgeon, not the other way
around,” said Cameron Piron, president and chief strategy officer of
Synaptive. “In developing the segmented white matter tract feature to
our Modus Plan, Synaptive aims to equip surgeons with the most
comprehensive view of each patient’s neuroanatomy so valuable energy
spent in the planning phase may be reflected in patient outcomes.”

Modus Plan, including its new automated tract segmentation feature,
represents Synaptive’s commitment to automation and product integration.
Modus Plan will be compatible with cranial implementations of
Synaptive’s suite of neurological and orthopedic care solutions.

About Synaptive Medical

Synaptive Medical Inc., a Toronto-based medical device and technology
company, designs hardware and software technologies that cross
traditional barriers in hospitals and improve patient care in and beyond
the operating room. Synaptive’s Modus V™ and integrated BrightMatter™
solutions—including surgical planning, navigation and visualization, and
an informatics platform—give leading clinicians and healthcare systems
the information they need to ensure the best possible outcomes for